Workers jumping from positive to negative and back without reason

I'm seeing workers jump from large positive to large negative numbers in one cycle for no reason. No waste in settlement, no active diseases. I have a + population with plenty of food and room. These jumps are unrealistic from +130 workers to -600 workers in one cycle. All settlement states in green. I can find no indication of why this is happening. I also notices the game is pulling more than 3GB of memory.

Can you please provide a save file where this occurs?

Closing as not enough information available. Please file a new bug if you have a save file and more info.