It is all greyed out except continue that is yellow (after reload that seem to be normal) but I cant click anything. Pressing ESC gets me back into game.
I think this happend because I edit the difficulty and turned off the ore sorter building and I think I also enabled quick fix feature as it was turned off (wanted a more harder game, but nice with backup plan). Not sure if this broke UI. Trying to reboot the game now. Lucky there seem to be an auto save fuction so my game is not lost. ALT+F4 and restarting the game resolved it. Once again I can click different options after pressing ESC ingame.