I know this might be too much as its a suggestion of a new natural resource "LEAD" but handling radioactive waste and material is very unfair in matters of transporting the items... You have to limit your builds to be small enough and even "accept" a little raditation to your population...
So... Why not add lead to create lead shielded pipes, belts, train wagons, stations... Plus you can use lead for batteries, which will be a heavy usage, plus add batteries to maintenance 2 maybe as part of the "change batteries" from time to time, and adding to big trucks and electric trains as part of the receipt as well... Maybe is a bit too much but would ease the radiation issue while moving radioactive material. Not block 100% but maybe 90% and give a higher penalty if these materials are not handled properly.